Thursday, July 30, 2009

The Prostate Test

TW: Leonhardt has turned into a go-to guy for health care. Here he uses prostate cancer to frame some of the cost/rationing/care challenges we face with our current system. There are multiple treatment varying widely in cost but with very unclear relative benefits. Even if say a $100K treatment is better than a $5K treatment at what point is it sufficiently better to warrant the cost? Who should make these determinations? One thing that is unclear from the article is exactly how these more expensive treatments are getting approved in the first place. Regardless these are questions which must be addressed if cost control is to ever become reality.

From David Leonhardt at NYT:
"...The prostate cancer test will determine whether President Obama and Congress put together a bill that begins to fix the fundamental problem with our medical system: the combination of soaring costs and mediocre results. If they don’t, the medical system will remain deeply troubled, no matter what other improvements they make.

...Right now, men with the most common form — slow-growing, early-stage prostate cancer — can choose from at least five different courses of treatment. The simplest is known as watchful waiting, which means doing nothing unless later tests show the cancer is worsening. More aggressive options include removing the prostate gland or receiving one of several forms of radiation. The latest treatment — proton radiation therapy — involves a proton accelerator that can be as big as a football field.

Some doctors swear by one treatment, others by another. But no one really knows which is best. Rigorous research has been scant. Above all, no serious study has found that the high-technology treatments do better at keeping men healthy and alive. Most die of something else before prostate cancer becomes a problem.

“No therapy has been shown superior to another,” an analysis by the RAND Corporation found. Dr. Michael Rawlins, the chairman of a British medical research institute, told me, “We’re not sure how good any of these treatments are.” When I asked Dr. Daniella Perlroth of Stanford University, who has studied the data, what she would recommend to a family member, she paused. Then she said, “Watchful waiting.”

But if the treatments have roughly similar benefits, they have very different prices. Watchful waiting costs just a few thousand dollars, in follow-up doctor visits and tests. Surgery to remove the prostate gland costs about $23,000. A targeted form of radiation, known as I.M.R.T., runs $50,000. Proton radiation therapy often exceeds $100,000.

And in our current fee-for-service medical system — in which doctors and hospitals are paid for how much care they provide, rather than how well they care for their patients — you can probably guess which treatments are becoming more popular: the ones that cost a lot of money.

Use of I.M.R.T. rose tenfold from 2002 to 2006, according to unpublished RAND data.

...You may never see this bill, but you’re paying it. It has raised your
health insurance premiums and left your employer with less money to give you a decent raise. The cost of prostate cancer care is one small reason that some companies have stopped offering health insurance. It is also one reason that medical costs are on a pace to make the federal government insolvent.

...The first step to passing the prostate cancer test is laying the groundwork to figure out what actually works. Incredibly, the only recent randomized trial comparing treatments is a 2005 study from Sweden. (It suggested that removing the prostate might benefit men under 65, which is consistent with the sensible notion that younger men are better candidates for some aggressive treatments.)

...To do that, health care reform will have to start to change the incentives in the medical system. We’ll have to start paying for quality, not volume.

On this score, health care economists tell me that they are troubled by Congress’s early work. They are hoping that the Senate Finance Committee will soon release a bill that does better. But as Ron Wyden, an Oregon Democrat on the committee, says, “There has not been adequate attention to changing the incentives that drive behavior.” One big reason is that the health care industry is lobbying hard for the status quo.

Plenty of good alternatives exist. Hospitals can be financially punished for making costly errors. Consumers can be given more choice of insurers, creating an incentive for them to sign up for a plan that doesn’t cover wasteful care. Doctors can be paid
a set fee for some conditions, adequate to cover the least expensive most effective treatment. (This is similar to what happens in other countries, where doctors are on salary rather than paid piecemeal — and medical care is much less expensive.)

Even if Congress did all this, we would still face tough decisions. Imagine if further prostate research showed that a $50,000 dose of targeted radiation did not extend life but did bring fewer side effects, like diarrhea, than other forms of radiation. Should Medicare spend billions to pay for targeted radiation? Or should it help prostate patients manage their diarrhea and then spend the billions on other kinds of care?

The answer isn’t obvious. But this much is: The current health care system is hard-wired to be bloated and inefficient. Doesn’t that seem like a problem that a once-in-a-generation effort to reform health care should address?"
http://www.nytimes.com/2009/07/08/business/economy/08leonhardt.html?scp=1&sq=david%20leonhardt%20prostate&st=cse

2 comments:

Anonymous said...

Gotta love hyperbole - yes, research accelerators are huge. medical treatment accelerators for proton are not. (the one at Loma Linda University Medical Center ( LLUMC) is 20ft in diameter - not tiny, granted, but about 7% the size of a "football field" diameter ring.
As for the costs - all these people that say that "conventional radiation (including IMRT)" are just as effective ignore one *major* difference: Quality of life.
The majority of treatments result in incontinence (listed as a *COMMON* side effect), and impotence (75% of men after 5 years)

Proton treatment spares healthy tissue in such a manner as to reduce or in many cases eliminate these effects.

So, yes, it may cost a little less - but ask the patient how much his sex life is worth, and you may be surprised. (and no, viagra and friends don't help - this is nerve damage)

Trey White said...

Taking Ms or Mr. Anon at their word I would ask the following:

1)Proton costs $100K or so (the commenter did not deny that) so can society afford $100K to retain male potency?

2)Should age matter?

3) By afford does that mean everyone? Or only folks able to afford insurance? Or over the age of 65 when Medicare kicks (then see Q#2)

The commenter may be right I suspect (would hope) a $100K treatment has more attributes than a $5K treatment. But this is about choices. It is easy to say yes when you are not paying directly but you are paying indirectly.